Status: Recruiting
The Effect of Retrograde Autologous Priming on Transfusion Requirements After Cardiac Surgery
The TheRAPy vanguard trial is a multicentre, multiple period randomized, cluster crossover vanguard trial testing the feasibility of a full-scale trial to evaluate whether a centre-based policy of routine use of RAP versus a policy of crystalloid priming reduces RBC transfusion for patients undergoing cardiac surgery on cardiopulmonary bypass. It will also provide information about key parameters of the TheRAPy full-scale trial.
Participants needed: 4,500
Trial details
Age: 10-110Biological sex: AllType: InterventionalSponsor: Population Health Research InstituteUpdated: Mar 4, 2025Locations: 4
Eligibility criteria
Hospitals completing >200 adult cardiac surgical cases a year; (ii) 95% of cardi... [+1]
Complete <=200 cardiac surgical cases. [+1]