Health Trials

Refractory B-Cell Lymphoma

3

Review clinical trials related to Refractory B-Cell Lymphoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Treatment of Relapsed or Refractory B-cell Lymphoma With Chimeric Antigen Receptor (CAR) T-cell Therapy Produced by a New Technology

The goal of this clinical trial is to to evaluate the safety and efficacy of TranspoCART19 in patients with relapsed/refractory B-lymphoma. The main questions it aims to answer are: Maximum tolerated dose (MTD) Response rates Participants will be treated with the investigational medicinal product and will be followed for 36 months.

Participants needed: 27
Trial details
Phase: Phase 1, Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: Instituto de Investigación Biomédica de SalamancaUpdated: Apr 16, 2026Locations: 8
Eligibility criteria

Patients diagnosed with relapsed or refractory B-cell lymphoma (Diffuse large B-... [+6]

Patients who, in the opinion of a physician, may benefit from other approved pot... [+15]

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Status: Recruiting

Study of CAR-T Therapy in Older Patients

This study is being done to find out how older patients respond to CAR-T cell therapy and how the treatment affects their quality of life. This is a quality of life study and participating in the study does not involve receiving any treatment, other than the standard treatment for participants' disease.

Participants needed: 154
Trial details
Age: 60+Biological sex: AllType: ObservationalSponsor: Memorial Sloan Kettering Cancer CenterUpdated: Apr 7, 2026Locations: 1
Eligibility criteria

are ≥60 years old (all cohorts) [+3]

Any prior commercial or investigational CAR T therapy (all cohorts) [+4]

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Status: Recruiting

Chidamide Combined With Linperlisibon for the Treatment of Refractory/Relapsed Follicular Lymphoma

To observe the safety and efficacy of Chidamide combined with Linperlisib in the treatment of refractory and relapsed follicular lymphoma.

Participants needed: 33
Trial details
Phase: Phase 2Age: 18+Biological sex: FemaleType: InterventionalSponsor: The First Affiliated Hospital of Xiamen UniversityUpdated: Feb 19, 2025Locations: 1
Eligibility criteria

The patients diagnosed with follicular lymphoma with grade 1-3a, have received a... [+6]

CNS involvement (current or previous). [+20]

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