Refractory Female Reproductive System Carcinoma

1

Review clinical trials related to Refractory Female Reproductive System Carcinoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

MUC1-Activated T Cells for the Treatment of Relapsed and Resistant Ovarian Cancer

This phase I trial tests the safety, side effects, best dose of MUC1-activated T cells in treating patients with ovarian cancer that has come back after a period of improvement (relapsed) or that remains despite treatment (resistant). T cells are infection fighting blood cells that can kill tumor cells. The T cells given in this study will come from the patient and are made in a laboratory to recognize MUC1, a protein on the surface of tumor cells that plays a key role in tumor cell growth. These MUC1-activated T cells may help the body's immune system identify and kill MUC1 expressing ovarian tumor cells.

Participants needed: 12
Trial details
Phase: Phase 1Age: 18+Biological sex: FemaleType: InterventionalSponsor: Mayo ClinicUpdated: Mar 16, 2026Locations: 1
Eligibility criteria

PRE-REGISTRATION: Age ≥ 18 years [+27]

Clinically unresolved central nervous system (CNS) metastases. NOTE: Patients wi... [+20]