Status: Recruiting
IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors
To find the highest tolerable dose of IACS-6274 that can be given alone, in combination with bevacizumab and paclitaxel, or in combination with capivasertib to patients who have solid tumors. The safety and tolerability of the study drug(s) will also be studied.
Participants needed: 54
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: M.D. Anderson Cancer CenterUpdated: Jun 1, 2026Locations: 1
Eligibility criteria
Provision of written informed consent prior to any study related procedures and... [+10]
Prior malignancy within the previous 2 years except for locally curable cancers... [+23]