Status: Recruiting
A Study of 19-28z/IL-18 in People With Acute Lymphoblastic Leukemia (ALL)
Participants will have a sample of their white blood cells, called T cells, collected using a procedure called leukapheresis. The collected T cells will be sent to a laboratory to be changed (modified) to become 19-28z/IL-18, the CAR T-cell therapy that participants will receive during the study. Making the participants' study therapy will take about 2-4 weeks.
Participants needed: 18
Trial details
Phase: Phase 1Age: 17+Biological sex: AllType: InterventionalSponsor: Memorial Sloan Kettering Cancer CenterUpdated: Feb 10, 2026Locations: 7
Eligibility criteria
For Philadelphia chromosome (Ph) negative B-ALL: Refractory or relapsed disease... [+14]
Concurrent active malignancy excluding: nonmelanoma skin cancer or localized sol... [+15]