Relapsed or Refractory AML and Other Hematologic Malignancies

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Review clinical trials related to Relapsed or Refractory AML and Other Hematologic Malignancies. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Phase I Clinical Trial of KK2845 in Patients With Relapsed or Refractory Acute Myeloid Leukemia and Other Hematologic Malignancies.

This is the first in human study of KK2845. This clinical trial consists of Part 1 (Dose Escalation) and Part 2 (Backfill). For patients with relapsed or refractory acute myeloid leukemia (AML) and other Hematologic Malignancies, in Part 1, the tolerability of KK2845 will be evaluated to determine the maximum tolerated dose (MTD). In Part 2, additional data will be collected by administering KK2845 at dose levels for which tolerability has been confirmed.

Participants needed: 156
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Kyowa Kirin Co., Ltd.Updated: Jul 1, 2026Locations: 17
Eligibility criteria

Patients with a confirmed diagnosis of AML according to the WHO classification (... [+19]

Patients who are diagnosed with APL. [+33]