Relapsed or Refractory Peripheral T-Cell Lymphoma

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Review clinical trials related to Relapsed or Refractory Peripheral T-Cell Lymphoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Adebrelimab Combined With SHR2554 in Relapsed/Refractory PTCL and NK/T-Cell Lymphoma

To evaluate the safety of adebrelimab combined with SHR2554 in the treatment of relapsed or refractory peripheral T-cell lymphoma (PTCL) and NK/T-cell lymphoma (NKTCL), to determine the recommended Phase 2 dose (RP2D) of the combination regimen, and to assess preliminary efficacy.

Participants needed: 40
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Sun Yat-sen UniversityUpdated: May 29, 2026Locations: 1
Eligibility criteria

Age ≥18 years old,regardless of gender; [+20]

Pregnant or lactating women; [+26]

Status: Not yet recruiting

Mitoxantrone Hydrochloride Liposome and Enlonstobart Combination Treatment in Patients With Relapsed or Refractory Peripheral T Cell Lymphoma (PTCL)

To evaluate the safety of mitoxantrone hydrochloride liposome combined with enlonstobart in the treatment of relapsed or refractory peripheral T-cell lymphoma, to determine the optimal dosage of mitoxantrone hydrochloride liposome within the combination regimen, and to assess the efficacy of the combined therapy.

Participants needed: 43
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Sun Yat-Sen University Cancer CenterUpdated: Dec 17, 2025
Eligibility criteria

Peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS); [+13]

Patients with hemophagocytic lymphohistiocytosis; [+21]

Status: Recruiting

Chidamide in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (R/R PTCL)

This is a phase II, open-label, non-randomized, single-arm, multicenter study to evaluate the efficacy, safety, and PK of chidamide in patients with R/R PTCL.

Participants needed: 33
Trial details
Phase: Phase 2Age: 20-75Biological sex: AllType: InterventionalSponsor: Great Novel Therapeutics Biotech & Medicals CorporationUpdated: Mar 11, 2025Locations: 5
Eligibility criteria

Histopathological diagnosis, made by the investigator, of the following PTCL sub... [+8]

Females who are pregnant or breastfeeding, or females of childbearing potential... [+16]