Renal AL Amyloidosis

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Review clinical trials related to Renal AL Amyloidosis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

DapagliFLOzin in Renal AL Amyloidosis (FLORAL)

The goal of this clinical trial is to learn if an oral drug called dapagliflozin is safe and can reduce high protein levels in the urine of patients with renal amyloid light-chain (AL) amyloidosis using a decentralized study design. Participants will be: * screened for the trial via an online platform * contacted by study personal to obtain electronic consent * enrolled in the trial if eligible and consented * contacted by study personal for further instructions and directions * sent dapagliflozin oral medication (supplied by the site pharmacy) * followed up regularly with the study team via telemedicine or other online avenues * monitored using lab work, inquiries about side effects and assessment of protocol adherence at 1 month, 3 months and 6 months * continue treatment for 6 months

Participants needed: 20
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Barbara Ann Karmanos Cancer InstituteUpdated: Jun 26, 2026Locations: 1
Eligibility criteria

Provision of signed and dated informed consent form. [+6]

Either ongoing first line induction with anti-plasma cell therapy or ongoing pos... [+9]