Status: Not yet recruiting
Efficacy and Safety of Renal Denervation on Isolated Diastolic Hypertension
This study aims to evaluate the efficacy and safety of renal denervation (RDN) in patients with isolated diastolic hypertension (IDH). The randomized, double-blind, sham-controlled, multicenter clinical trial will recruit 124 participants (62 in the treatment group and 62 in the sham control group) to assess changes in mean 24-hour ambulatory diastolic blood pressure over a 6-month follow-up period. The study is expected to provide evidence for the use of RDN as a treatment for IDH.
Participants needed: 124
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Shanghai 10th People's HospitalUpdated: Feb 2, 2026Locations: 1
Eligibility criteria
Age ≥18 years, with no restriction on sex or ethnicity; [+2]
DBP ≥110 mmHg; [+8]