Repetitive Head Impacts

2

Review clinical trials related to Repetitive Head Impacts. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Monitoring Patients With Repetitive Head Impact With Gamma-glutamylcysteine Supplementation

The goal of this clinical trial is to test whether the gamma - glutamylcystiene (GGC) oral supplement can reach the brain and subsequently increase antioxidant glutathione (GSH) level in people with repetitive head impact (RHI). This will reduce the oxidative stress related injury in people with RHI.This unique study's main objective is to test the: 1. Change in GSH in brain and blood levels through GGC supplementation. 2. Change in the cognitive function in RHI patients due to GGC supplementation.

Participants needed: 30
Trial details
Phase: Phase 1Age: 30-70Biological sex: AllType: InterventionalSponsor: Pravat MandalUpdated: Jun 3, 2026Locations: 1
Eligibility criteria

Retired NFL player, retired Navy SEAL/army personnel with combat experience expo... [+3]

Presence of pacemakers, aneurysm clips, artificial heart valves, ear implants, m... [+8]

Status: Recruiting

RHI Interval Effects on Brain Health

Military service members frequently experience repetitive insults or impacts to the head (RHIs). The purpose of the proposed randomized controlled trial is to understand how time intervals affect neurological responses to repetitive subconcussive head impacts.

Participants needed: 102
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: Indiana UniversityUpdated: May 4, 2026Locations: 1
Eligibility criteria

Current soccer player (intercollegiate, club, intramural, recreational). [+2]

Any head, neck, or face injury within the 6 months prior to enrollment, includin... [+2]