Replacement Material

1

Review clinical trials related to Replacement Material. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Cryoneurolysis Prior to Total Knee Arthroplasty (CRYO-TKA Trial)

Approximately 20-30% of patients experience persistent pain after a Total Knee Arthroplasty (TKA). This study investigates whether percutaneous cryoneurolysis of genicular nerves can reduce pain and improve physical function when performed at least 24 hours before surgery. Participants will be randomized to receive either the cryoneurolysis procedure + TKA or TKA only. Results will be tracked for 6 months to see if the intervention improves long-term recovery and quality of life.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Attikon HospitalUpdated: Feb 20, 2026Locations: 1
Eligibility criteria

Adults ≥18 years undergoing primary TKA for osteoarthritis. [+2]

Cancer-related knee pain. [+2]