Status: Recruiting
Neoadjuvant/Adjuvant AK104 in Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon Cancer
This is a randomized, open-label, controlled, multicenter phase 3 study. All patients are resectable microsatellite instability-high (MSI-H) or mismatch repair-deficient (dMMR) colon cancer. The purpose of this study is to evaluate the efficacy and safety of neoadjuvant/adjuvant treatment of AK104 (Cadonilimab) versus adjuvant chemotherapy in patients with resectable MSI-H/dMMR colon cancer.
Participants needed: 386
Trial details
Phase: Phase 3Age: 18-75Biological sex: AllType: InterventionalSponsor: AkesoUpdated: Apr 22, 2026Locations: 1
Eligibility criteria
Voluntarily sign a written ICF. [+9]
Previously received any anti-tumor treatment for the study disease, including su... [+10]