Reversible Pulpitis

8

Review clinical trials related to Reversible Pulpitis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Influence of Proximal Caries on Outcome of Direct Pulp Capping in Permanent Mandibular Molars With Reversible Pulpitis

The aim of the study is to assess the Influence of proximal caries on outcome of direct pulp capping in permanent mandibular molars with sign of reversible pulpitis. objective- Primary objective- To evaluate and compare the clinical and radiographic outcome of Direct pulp capping in mandibular molars with occlusal and proximal carious lesions. Secondary objective- To evaluate and compare 1.OHRQoL after Direct pulp capping in occlusal and proximal lesion. 2. Postoperative pain, after Direct pulp capping in occlusal and proximal lesion Subjects of age group 15 - 40 yrs will be included and divided into two groups 1) Permanent mature molars with proximal carious lesion 2)Permanent mature molars with occlusal carious lesion.

Participants needed: 154
Trial details
Age: 15-40Biological sex: AllType: InterventionalSponsor: Postgraduate Institute of Dental Sciences RohtakUpdated: Jun 10, 2026Locations: 1
Eligibility criteria

Mature permanent mandibular molars with extremely deep caries that penetrate the... [+2]

Mechanical or pulp exposure due to trauma [+5]

Status: Recruiting

Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker

This prospective controlled clinical trial investigates whether metabolic biomarkers measured in pulpal blood at the time of carious pulp exposure can predict the 12-month outcomes of vital pulp treatment in symptomatic permanent teeth. Eligible patients aged 16-50 years presenting with deep carious pulp exposure will undergo vital pulp therapy (partial pulpotomy or full pulpotomy). Pulpal blood samples will be collected at the time of exposure and analyzed using High-Performance Liquid Chromatography (HPLC). Treatment outcomes will be assessed clinically and radiographically at 12 months. The study aims to identify objective, measurable biomarkers that can improve pulpal diagnosis and guide clinical decision-making in vital pulp therapy.

Participants needed: 60
Trial details
Age: 16-50Biological sex: AllType: InterventionalSponsor: Abeer Ghalib Abdul-khaliqUpdated: Apr 1, 2026Locations: 1
Eligibility criteria

Age range of 16-50 years. [+4]

Teeth with unrestorable large defects or the need for RCT for aesthetic reasons; [+5]

Status: Not yet recruiting

Comparative Evaluation of Calcium Silicate-doped Treated Dentin Matrix and Mineral Trioxide Aggregate as Miniature Pulpotomy Biomaterials in Deep Carious Lesions

AIM: To compare the efficacy of a Novel calcium silicate doped treated dentin matrix and Mineral Trioxide aggregate as biomaterials for miniature pulpotomy. OBJECTIVES: Primary objective: To evaluate the efficacy of calcium silicate-doped human-treated dentin matrix (CaSi+hTDM) compared to Mineral Trioxide Aggregate (MTA) in maintaining pulp vitality using cold testing following Miniature Pulpotomy (MP) in deep and extremely deep carious lesions with reversible pulpitis in 14- to 35-year-old patients reporting to Department of Dentistry, AIIMS Nagpur. Secondary objectives: 1. To evaluate patient-reported outcomes such as pain, swelling, sinus tract etc. post-operatively. 2. To determine the clinical success rates of both materials by assessing the Periapical index of healing over a 6 months follow-up period. NULL HYPOTHESIS: The null hypothesis (H0) is that there is no difference between CaSi+hTDM and MTA in maintaining pulp vitality when used as a Miniature Pulpotomy (MP) biomaterial in carious lesions.

Participants needed: 56
Trial details
Age: 14-35Biological sex: AllType: InterventionalSponsor: All India Institute of Medical SciencesUpdated: Mar 10, 2026Locations: 2
Eligibility criteria

The clinical diagnosis of reversible pulpitis characterized by mild pain (on Num... [+3]

A history of spontaneous unprovoked toothache, pain on percussion, a sinus tract... [+5]

Status: Recruiting

Comparative Evaluation of Indirect vs. Direct Pulp Capping in Deep Carious Mandibular Molars

Aim: To compare the outcome of indirect and direct pulp capping after partial or complete caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis. Objectives: 1. To evaluate the clinical and radiographic success of indirect pulp capping after partial caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis. 2. To evaluate the clinical and radiographic success of direct pulp capping after complete caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis. 3. To evaluate pain incidence and severity after indirect and direct pulp capping after partial and complete caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis.

Participants needed: 106
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Postgraduate Institute of Dental Sciences RohtakUpdated: Feb 12, 2026Locations: 1
Eligibility criteria

The patient should be ≥18 years of age. [+7]

Teeth with immature roots. [+7]

Status: Not yet recruiting

Outcome of Direct Pulp Capping and Partial Pulpotomy in Reversible Pulpitis

AIM: -The aim of the study is to compare the outcome of Direct Pulp Capping and Partial Pulpotomy in mature permanent teeth with Reversible Pulpitis OBJECTIVES: - Primary Objective: to compare the difference in clinical and radiographic outcome of direct pulp capping and partial pulpotomy in mature permanent teeth with Reversible Pulpitis. Secondary objective: To evaluate and compare postoperative pain after Direct Pulp Capping and Partial Pulpotomy in teeth with Reversible Pulpitis STUDY GROUPS: - Subjects of age group 15 to 40 years will be included and divided into two groups 1. Direct Pulp Capping in Permanent mature molars with Reversible Pulpitis 2. Partial Pulpotomy in Permanent mature molars with Reversible Pulpitis

Participants needed: 138
Trial details
Age: 15-40Biological sex: AllType: InterventionalSponsor: Postgraduate Institute of Dental Sciences RohtakUpdated: Dec 23, 2025Locations: 1
Eligibility criteria

Patients aged 15-40 years. [+5]

Non restorable teeth [+11]

Status: Recruiting

Assessment of Pain and Anxiety During Infiltration Anesthesia Using Dental Anesthesia Injector Versus Conventional Syringe in Pediatric Patients

This randomized controlled trial is conducted on pediatric dental patients to compare the effectiveness of local anesthesia administered using a dental anesthesia injector device versus the traditional syringe method. The study aims to assess and compare pain and anxiety levels associated with both methods, using both subjective (self-reported) and objective measures. The goal is to identify an alternative technique that minimizes pain and anxiety in pediatric dental patients.

Participants needed: 40
Trial details
Age: 6-8Biological sex: AllType: InterventionalSponsor: Ain Shams UniversityUpdated: Aug 3, 2025Locations: 2
Eligibility criteria

normal healthy patients (ASA I) [+3]

Presence of gingivitis, dental abscess, facial trauma/ injury [+2]

Status: Recruiting

The Effect of Different Risk Factors on the Success Rate of VPT

This study aims to evaluate the effectiveness of various vital pulp therapy (VPT) methods, such as direct pulp capping, partial pulpotomy, and total pulpotomy, in maintaining pulp vitality following pulp exposure. It explores the success rates of these treatments compared and investigates co-factors influencing these rates, including age. This prospective cohort study involves patients over 18 with restorable teeth and exposed pulp chambers. Success is measured through clinical and radiological criteria over a follow-up period of up to four years. The study also aims to identify if there's an age threshold affecting the preference for VPT over root canal therapy.

Participants needed: 400
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Semmelweis UniversityUpdated: Mar 6, 2025Locations: 1Duration: 4 Years
Eligibility criteria

Patients over 18 years of age who have at least one tooth with a pulp chamber th... [+3]

Internal/external resorption in the tooth [+8]

Status: Not yet recruiting

Caries Location and Its Effect on the Success Rate of Indirect Pulp Treatment in Primary Molars

The following study will be created to evaluate how the location of caries affects the effectiveness of indirect pulp treatment in primary molars. aiding in the development of evidence-based recommendations for pediatric dentists.

Participants needed: 50
Trial details
Age: 3-7Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Nov 5, 2024
Eligibility criteria

Children aged between 3-7 years [+7]

Clinical symptoms or history indicating irreversible pulpitis as (spontaneous pa... [+7]