Reward Learning

1

Review clinical trials related to Reward Learning. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

The Influence of Obesity and Insulin Sensitivity on Reward Processing and Decision Making

Reward learning and decision-making processes, which operate largely outside of conscious control, shape food choices and eating behaviors. Excess adiposity is associated with differences in brain structure and functional connectivity underlying these processes, and insulin resistance, which commonly co-occurs with excess adiposity, has been linked with dopamine signaling that is crucial for these processes. However, whether and how excess adiposity and insulin resistance affect reward learning and decision-making remains poorly understood. This study will address that gap, examining the effects of excess adiposity and insulin resistance, and their interaction, on processes of reward learning and decision-making in food-specific and general contexts.

Participants needed: 50
Trial details
Age: 18-45Biological sex: AllType: InterventionalSponsor: Virginia Polytechnic Institute and State UniversityUpdated: Jun 10, 2026
Eligibility criteria

18 to 45 years of age [+4]

BMI < 18.5 or > 40 kg/m2 [+14]