Status: Recruiting
Therapeutic Drug Monitoring for Linezolid in the Treatment of Rifampin-resistant Tuberculosis
This study is a two-arm, pragmatic, open-label, randomized clinical trial to determine the efficacy of Therapeutic Drug Monitoring (TDM) in preventing premature discontinuation of Linezolid (LZD) in participants with Rifampicin-resistant tuberculosis (RR-TB). Following the initiation of treatment, participants will be monitored throughout the approximate 6-month duration of RR-TB therapy.
Participants needed: 280
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Albert Einstein College of MedicineUpdated: May 4, 2026Locations: 1
Eligibility criteria
Adult male or female patient > 18 years of age [+5]
Severe medical condition with expected death in the next 7 days [+4]