Safety and Tolerability in Healthy Volunteers

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Review clinical trials related to Safety and Tolerability in Healthy Volunteers. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Safety and User Experience of BP-CBB

This study is the first-in human study for the food ingredient BP-CBB and aims aims to build on the excellent safety and tolerability observed in the extensive food safety assessment performed for BP-CBB, as well as the consumer experience with using the product, and to set the scene for future human studies documenting the health-benefits of daily supplementation with BP-CBB for diverse populations.

Participants needed: 60
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Bactolife A/SUpdated: Jun 18, 2026Locations: 1
Eligibility criteria

Be able to give written informed consent. [+5]

Participants who are pregnant or wish to become pregnant during the study or who... [+23]

Status: Not yet recruiting

A Study Testing the Effects of Different THC Doses on Psychological and Biological Function

The goal of this clinical trial is to learn how a investigational medicinal product (THC) affects psychological and physical responses in healthy adults with prior cannabis use experience. The main questions it aims to answer are: \- How do different dose levels of the investigational medicinal product (THC) influence short-term subjective and physiological responses? Researchers will compare three dose levels of the study drug to a placebo (a look-alike substance with no active ingredient) to see how responses vary across sessions. Participants will: * Attend four in-person study visits, each involving a single dose of either the study drug or placebo * Complete questionnaires about their moment-to-moment experiences * Have their heart rate, blood pressure, and other physical measures monitored * Undergo serial blood sampling to measure circulating biomarkers

Participants needed: 24
Trial details
Phase: Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: University of CalgaryUpdated: Jan 16, 2026Locations: 1
Eligibility criteria

Adults aged 18-55 [+3]

Family history (first- or second-degree relatives) of bipolar disorder, psychosi... [+2]

Status: Recruiting

Effects of Lentil Protein Hydrolysate on Blood Pressure Control, Vascular Function and Exercise Performance

Examining the safety and tolerability of Lentil Protein Hydrolysate in healthy males and females whilst exploring the effects of a dose range on blood pressure control and vascular function and exercise performance

Participants needed: 48
Trial details
Age: 18-45Biological sex: AllType: InterventionalSponsor: Nuritas LtdUpdated: Dec 16, 2025Locations: 1
Eligibility criteria

Willing to provide written and dated informed consent to participate in the stud... [+7]

Subjects having a known allergy or hypersensitivity to any of the ingredients in... [+10]