Scleroderma, Localized

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Review clinical trials related to Scleroderma, Localized. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA Repository

The Morphea in Adults and Children (MAC) cohort is the first registry for both children and adults with morphea (also known as localized scleroderma) in the country. The purpose of the registry is to learn more about morphea, specifically: * How morphea behaves over time * How frequently specific problems occur along with morphea (for example, arthritis) * Whether morphea has an autoimmune background

Participants needed: 500
Trial details
Age: Up to 90Biological sex: AllType: ObservationalSponsor: University of Texas Southwestern Medical CenterUpdated: May 12, 2026Locations: 1Duration: 6 Years
Eligibility criteria

Patient must have a clinical diagnosis of morphea confirmed by the primary inves... [+7]

Status: Recruiting

Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach in Children and Adults Diagnosed With Scleroderma

This study aims to investigate the effectiveness of BETY, an exercise approach based on the biopsychosocial model, in children and adults diagnosed with scleroderma.

Participants needed: 48
Trial details
Age: 7+Biological sex: AllType: InterventionalSponsor: Hacettepe UniversityUpdated: Dec 18, 2025Locations: 1
Eligibility criteria

Cases diagnosed with scleroderma, [+1]

Advanced heart/lung/liver/kidney disease, neurological disease, and malignancies [+10]

Status: Recruiting

Patients Diagnosed With Scleroderma: Physical Performance and Functionality

Physical functionality and performance are important for individuals diagnosed with scleroderma. There is a need to address children and adults diagnosed with scleroderma comprehensively and to evaluate them on a biopsychosocial basis to support their disease management. In light of all this literature, the aim was to evaluate the biopsychosocial characteristics of both pediatric and adult scleroderma patients and to examine their physical performance and functionality. Additionally, this study aims to identify effective tests that can be used in future research to assess physical performance and functionality in individuals diagnosed with scleroderma.

Participants needed: 50
Trial details
Age: 7+Biological sex: AllType: ObservationalSponsor: Hacettepe UniversityUpdated: Sep 19, 2025Locations: 1Duration: 2 Weeks
Eligibility criteria

Cases diagnosed with scleroderma, [+1]

Advanced heart/lung/liver/kidney disease, neurological disease, and malignancies [+9]

Status: Recruiting

Patients Diagnosed With Scleroderma and Their Chewing and Swallowing Performance

It is recommended to focus on the physical functionality, chewing, and swallowing performance of individuals diagnosed with scleroderma. There is a need to address children and adults diagnosed with scleroderma comprehensively and to evaluate them on a biopsychosocial basis to support their disease management. The aim was to assess the biopsychosocial characteristics of both children and adults diagnosed with scleroderma and to examine their chewing and swallowing performance. Additionally, this study aims to identify effective scales that can be used in future research to assess chewing and swallowing in individuals diagnosed with scleroderma.

Participants needed: 50
Trial details
Age: 7+Biological sex: AllType: ObservationalSponsor: Hacettepe UniversityUpdated: Sep 19, 2025Locations: 1Duration: 2 Weeks
Eligibility criteria

Cases diagnosed with scleroderma, [+1]

Advanced heart/lung/liver/kidney disease, neurological disease, and malignancies [+9]