Health Trials

Second-line Therapy

2

Review clinical trials related to Second-line Therapy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Carilizumab and Albumin Paclitaxel for Second-line Treatment of Advanced Gastric Cancer

This study was an open, single center, prospective cohort study design. Subjects with advanced gastric cancer who had received first-line chemotherapy (cohort 1) and systematic chemotherapy combined with immunotherapy (cohort 2) were included in this study. 20 cases were included in each population, and a total of 40 subjects were planned to be included.

Participants needed: 40
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Shandong Tumor HospitalUpdated: Mar 13, 2026Locations: 1
Eligibility criteria

Age range: 18 to 75 years old, both male and female are acceptable; [+9]

History of gastrointestinal perforation and/or fistula within 6 months prior to... [+22]

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Status: Not yet recruiting

A Single-Arm, Phase II Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan in Second-Line and Subsequent Treatments for Advanced Thymic Epithelial Tumors

This is a single-arm, phase II study to evaluate the efficacy and safety of Sacituzumab Tirumotecan, a TROP2-directed antibody-drug conjugate, in patients with advanced thymic epithelial tumors who have received second-line or later therapy.

Participants needed: 38
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Sun Yat-sen UniversityUpdated: Jan 15, 2026
Eligibility criteria

Advanced (unresectable or metastatic) thymic epithelial tumor confirmed by histo... [+10]

Previously received targeted drug therapy with Lucasatuzumab. [+16]

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