Status: Recruiting
Etiology and Treatment of Neonatal Seizure
Genetic diagnosis for neonates suffering from epilepsy has important implications for treatment, prognosis, and development of precision medicine strategies. Investigator performed exome sequencing (ES) or targeted sequencing on neonates with seizure onset within the first month of life. Investigator subgrouped our patients based on the onset age of seizure into neonatal and before 1 year (1-12 months), to compare the clinical and genetic features and treatment strategies.
Participants needed: 2,000
Trial details
Age: Up to 12Biological sex: AllType: ObservationalSponsor: Children's Hospital of Fudan UniversityUpdated: Mar 16, 2026Locations: 1
Eligibility criteria
severe seizures in neonates or generalized epilepsy or intractable epilepsy in i... [+2]
Patients were excluded if they had traumas, central nervous system infections, h...