Health Trials

Severe Eosinophilic ACOS (Asthma-COPD Overlap)

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Review clinical trials related to Severe Eosinophilic ACOS (Asthma-COPD Overlap). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Blood Exosomal Multi-omics and Lung Radiomics for Predicting Efficacy and Prognosis of Severe Eosinophilic ACOS With Biologics

Firstly, to screen blood exosomal multi-omics (transcriptomics, proteomics, metabolomics) and lung radiomics (HRCT, Xe129MRI) biomarkers that can predict efficacy and prognosis in severe eosinophilic ACOS (asthma-COPD overlap) patients treated with different biologics (benralizumab, mepolizumab, dupilumab). Then, to prospectively follow patients for 48 weeks after biologic initiation and collect clinical data, blood samples, and imaging features. Finally, to build a multi-dimensional predictive model for efficacy and prognosis of severe eosinophilic ACOS.

Participants needed: 500
Trial details
Age: 14+Biological sex: AllType: ObservationalSponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyUpdated: May 22, 2026Locations: 1
Eligibility criteria

Age ≥ 14 years [+3]

Currently participating in any other interventional clinical trial [+3]

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