Health Trials

Severe Hemophilia A Without Inhibitor

2

Review clinical trials related to Severe Hemophilia A Without Inhibitor. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study on the Bone-health Effectiveness of Applying Recombinant Factor VIII Fc (rFVIIIFc) to Patients With Hemophilia A (Prototype A)

Study Objectives\* 1. Provide a systematic evaluation of the treatment outcomes in patients with hemophilia A 2. Emphasize the importance and clinical benefits of rFVIII-Fc in joint and bone health. 3. Compare the clinical outcomes from 1 year before and after switching to EHL. 4. Exploratory: Identify biomarkers that could provide more useful and convenient evaluations of joint and bone health. (Time-saving and easy to monitor)

Participants needed: 45
Trial details
Biological sex: MaleType: ObservationalSponsor: Tri-Service General HospitalUpdated: Apr 10, 2024Locations: 1
Eligibility criteria

Patients with severe hemophilia A (all ages). [+3]

Participants of other interventional studies. [+4]

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Status: Recruiting

Dynamics of the Anti-factor VIII Antibody Signature During Treatment With Emicizumab

The goal of this observational study is to learn about the changes of antibodies and inhibitors against the coagulation factor VIII in patients with severe hemophilia A receiving emicizumab therapy. No additional visits or procedures are planned. Patients in this study will continue to receive their routine care and analysis will be done from left over samples from routine visits.

Participants needed: 100
Trial details
Biological sex: AllType: ObservationalSponsor: Christoph KönigsUpdated: Jul 10, 2023Locations: 1
Eligibility criteria

Severe congenital hemophilia A (CHA) [+2]

No therapy with emicizumab [+2]

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