Severe Sickle Cell Disease

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Review clinical trials related to Severe Sickle Cell Disease. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

This study is designed to estimate the efficacy and toxicity of familial HLA mismatched bone marrow transplants in patients with non-malignant disease who are less than 21 years of age and could benefit from the procedure.

Participants needed: 29
Trial details
Phase: Phase 1, Phase 2Age: 1-21Biological sex: AllType: InterventionalSponsor: Washington University School of MedicineUpdated: May 29, 2026Locations: 4
Eligibility criteria

Nonmalignant disorder requiring bone marrow transplant including bone marrow fai... [+17]

Patients who have an HLA-identical sibling who is able and willing to donate bon... [+7]