Severe Tricuspid Valve Regurgitation

2

Review clinical trials related to Severe Tricuspid Valve Regurgitation. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Patients With Severe TrIcuspid Regurgitation After triCvALve System Implantation

International Registry to collect patients with severe TR undergoing TricValve implantation from multiple Italian and European centers, aimed at: * Assessing the effect of TricValve implantation on cardiovascular and all-cause mortality, HF rehospitalization, renal function, functional capacity and quality of life. * Clarifying the haemodynamic effects of TricValve implantation and investigating their pathophysiological implications.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Azienda Ospedaliero, Universitaria PisanaUpdated: May 11, 2026Locations: 1Duration: 3 Years
Eligibility criteria

The subject must be 18 years of age or older [+5]

Known significant intracardiac shunt (e.g. ventricular septal defect) or congeni... [+12]

Status: Not yet recruiting

The STTAR-US Study: A Pivotal Study of Transcatheter Tricuspid Annular Repair in the US

Purpose of this clinical study is to demonstrate the safety and efficacy of MIA-T system in improving clinical outcomes in symptomatic patients with severe tricuspid regurgitation (TR grade ≥3) despite optimal medical therapy, who have been determined by the site's local heart team to be at intermediate or greater estimated risk for mortality and morbidity with tricuspid valve surgery.

Participants needed: 600
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Micro Interventional DevicesUpdated: Nov 26, 2025
Eligibility criteria

Subject has severe functional TR (≥ 3). Note: If any cardiac procedure(s) occur... [+2]

Systolic pulmonary artery pressure (sPAP) > 70 mmHg or > 5 wood units (WU) despi... [+10]