Severly Acutely Malnourished Children

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Review clinical trials related to Severly Acutely Malnourished Children. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Maximizing the Benefits of Iron in Ready-to-Use Therapeutic Foods for Malnourished Children in Kenya

Reports from the Kenya Red Cross Society (KRCS) in Kwale County, southern Kenya, indicate a limited impact of Ready-to-Use Therapeutic Foods (RUTFs) on malnutrition or anemia. The current RUTF formulation may have an excessively high iron content. In severely acutely malnourished (SAM) children, iron cannot be properly absorbed, leading to life-threatening diarrhea. The overall aim of this project is to develop an improved RUTF treatment that addresses acute malnutrition and anemia in children, ensuring both safety and efficacy. Specifically, to assess the impact of malnutrition on fractional iron absorption (FIA) from RUTFs in children, by comparing healthy children to those with acute malnutrition and by tracking changes in FIA in malnourished children over the course of treatment.

Participants needed: 68
Trial details
Age: 12-54Biological sex: AllType: InterventionalSponsor: ETH ZurichUpdated: Jan 2, 2026Locations: 2
Eligibility criteria

severe acute malnutrition (SAM): WHZ < -3.0 [+2]

Hemoglobin ≤7 g/dL [+1]