Silodosin

1

Review clinical trials related to Silodosin. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Clinical Outcomes and Ejaculatory Function in BPO Patients Treated With Silodosin

This observational study aims to evaluate the relationship between silodosin-induced anejaculation and clinical outcomes in male patients with benign prostatic obstruction (BPO). Silodosin is a commonly used alpha-blocker for lower urinary tract symptoms (LUTS). However, it may cause ejaculatory dysfunction, particularly anejaculation. In this study, patients receiving silodosin for the first time will be grouped based on whether they experience anejaculation or not. Treatment response will be assessed using urinary flow rate, post-void residual urine, and International Prostate Symptom Score (IPSS). Sexual function will be evaluated using the International Index of Erectile Function-5 (IIEF-5) before and after treatment. The study aims to explore whether the presence of anejaculation is associated with improved symptom relief or differences in sexual health.

Participants needed: 100
Trial details
Age: 40+Biological sex: MaleType: ObservationalSponsor: Marmara UniversityUpdated: Jun 5, 2025
Eligibility criteria

Male patients aged 40 years or older [+4]

History of prior treatment with silodosin or other α-blockers in the last 3 mont... [+6]