Sinusitis

4

Review clinical trials related to Sinusitis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Complicated Infections in Otorhinolaryngology

This observational study aims to learn more about complicated infections treated by otorhinolaryngologists. The main questions to answer are: * What is the management of complicated sinonasal infections in Ljubljana, Slovenia, * What is the management of complicated ear and temporal bone infections in Ljubljana, Slovenia, * What is the management of complicated neck soft tissue infections in Ljubljana, Slovenia, * What is the management of complicated laryngeal infections in Ljubljana, Slovenia Participants will receive standard treatment according to the established evidence-based clinical practice.

Participants needed: 2,550
Trial details
Biological sex: AllType: ObservationalSponsor: University Medical Centre LjubljanaUpdated: Apr 29, 2026Locations: 1Duration: 1 Year
Eligibility criteria

Diagnoses: rhinitis AND/OR sinusitis AND/OR facial cellulitis AND/OR facial absc... [+1]

disagreement of the patient and/or parents (or legal guardians) with inclusion i... [+1]

Status: Recruiting

In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps

Chronic rhinosinusitis, also called chronic sinusitis, is a very common life-long disease affecting over 5% of the Canadian population. Its symptoms, including daily facial pain and headache, an inability to breath through the nose and complete smell loss, regularly impair one's ability to work and to enjoy and participate in daily activities. The annual cost of chronic sinusitis to Canada is estimated at $1.3 billion while the government pays an estimated $860 million yearly for chronic sinusitis treatment. Chronic sinusitis with polyps, the most common type of chronic sinusitis, is usually treated with a combination of medications and surgery. Until now, surgical treatment has only been performed in the operating room, at a cost of about $3500 per procedure. But, recent studies have shown that a new procedure, "in-clinic polyp removal", can provide an improvement in patient symptoms to levels equal to those for sinus surgery performed in a hospital operating room. Moreover, in clinic polyp removal has additional advantages including a shorter procedure recovery time, a significantly lower cost to the health care system (about one-tenth the cost or $450), and a shorter wait time for treatment. With the proposed pragmatic trial, the investigators will determine whether the in clinic polyp removal procedure is as good as sinus surgery in the operating room at controlling patient symptoms of chronic sinusitis. The investigators will also determine the cost and health-benefits for a patient, the healthcare system and for society of in clinic polyp removal in comparison to sinus surgery done in a hospital operating room. The investigators will then know if this new treatment, in clinic polyp removal, can replace sinus surgery as the standard of care for these patients.

Participants needed: 140
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Ottawa Hospital Research InstituteUpdated: Dec 30, 2025Locations: 4
Eligibility criteria

Age 18 years or older [+6]

Women who are pregnant or breast feeding as per patient's report [+20]

Status: Recruiting

How OMT Benefits Newly Diagnosed Patients With Respiratory Illness When Given Alongside Other Standard Care.

This study is to see Osteopathic Manipulative Therapy, or OMT, can aid in treating patients being seen for respiratory illness and associated symptoms. The hypothesis is that the addition of OMT therapy, alongside other standard care (such as a medication), can help lessen patient symptoms sooner than just other treatment alone, and the duration of the condition will shorten as well.

Participants needed: 68
Trial details
Age: 65-100Biological sex: AllType: InterventionalSponsor: Geisinger ClinicUpdated: Jul 8, 2025Locations: 1
Eligibility criteria

Patients being seen for respiratory illness symptoms at Geisinger 65-Forward Buc... [+2]

Patients that have a healing fracture, including the spine, pelvis, shoulder, ri... [+2]

Status: Not yet recruiting

Efficacy of Two Nasal Products Based on Diluted Seawater in the Treatment of Upper Respiratory Infections/Conditions

The goal of this interventional clinical trial is to test the safety and efficacy of two medical devices in subjects aged from 3 months old for the treatment of colds, rhinitis, sinusitis, and other upper respiratory infections/conditions for 7 days.

Participants needed: 91
Trial details
Age: 3+Biological sex: AllType: InterventionalSponsor: YSLabUpdated: Aug 2, 2024
Eligibility criteria

Autonomous adult, or minor with the consent of their legal representative [+5]

Person not showing cold symptoms, particularly no nasal congestion (chronic dry... [+6]