Status: Recruiting
Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer
This is a single arm, Phase II trial involving the use of atezolizumab plus platinum and etoposide for patients with locally advanced urothelial cancer. The primary goal of this trial is to assess the pathologic complete response rate at cystectomy in patients after being treated with a combination therapy of atezolizumab, platinum, and etoposide.
Participants needed: 63
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsUpdated: Jun 25, 2026Locations: 2
Eligibility criteria
Histologically confirmed invasive carcinoma of the bladder with pure, or any com... [+22]
No prior systemic treatment for small-cell bladder cancer (SCBC) [+32]