Health Trials

Small Lymphocytic Leukemia (SLL)

2

Review clinical trials related to Small Lymphocytic Leukemia (SLL). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of Zanubrutinib, Obinutuzumab, and Venetoclax in Patients With Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL)

The purpose of this study is to determine the rate of minimum residual disease (MRD) negative response (i.e. the rate of no evidence of disease) of the study drugs, zanubrutinib, obinutuzumab, and venetoclax, given in combination as a treatment for CLL and/or SLL.

Participants needed: 230
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Memorial Sloan Kettering Cancer CenterUpdated: May 7, 2026Locations: 8
Eligibility criteria

Ability and willingness to comply with the requirements of the study protocol [+17]

Known active histological transformation from CLL to an aggressive lymphoma (i.e... [+27]

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Status: Recruiting

Phase II Study of Combined Pirtobrutinib, Venetoclax and Obinutuzumab (PVO) Time-limited Treatment for Patients With Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL).

To learn if the drug combination pirtobrutinib, venetoclax, and obinutuzumab can help to control relapsed CLL/SLL.

Participants needed: 40
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: M.D. Anderson Cancer CenterUpdated: Nov 6, 2025Locations: 1
Eligibility criteria

Age 18 years or older. [+21]

Participants who experienced progression of disease according to 2018 iwCLL crit... [+35]

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