Soft Tissue

3

Review clinical trials related to Soft Tissue. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluation of Multilayered PRF in Comparison With Connective Tissue Graft by Sohn Poncho's Technique on Peri-implant Mucosal Enhancement in the Esthetic Zone

An effective biological seal is crucial for protecting and supporting dental implants, particularly in the anterior region for the desired esthetic outcome.PRF membrane and CTG has been utilized to improve peri-implant soft tissue thickness and increase the width of keratinized tissue around dental implants. The stability of the PRF membrane is maintained by securing it with the healing abutment of the implant. While a few longitudinal studies have assessed the benefits of using PRF membrane with Sohn's Poncho technique in the posterior region, its effectiveness in the anterior region of the mouth remains to be evaluated.

Participants needed: 26
Trial details
Age: 20-70Biological sex: AllType: InterventionalSponsor: Gulf Medical UniversityUpdated: Jun 16, 2026Locations: 1
Eligibility criteria

Patients with single bounded missing tooth in the esthetic zone Patients in the...

Status: Recruiting

Pediatric PET/MR Image Registry

The purpose of this study is to compare whole body magnetic resonance (MR) imaging, whole body positron emission tomography (PET)/MR imaging, and (if available) PET/Computed Tomography (CT) imaging for the diagnosis of tumors in children and young adults. Sensitivities, specificities and diagnostic accuracies of the different imaging modalities will be compared for significant differences.

Participants needed: 100
Trial details
Age: Up to 40Biological sex: AllType: ObservationalSponsor: Stanford UniversityUpdated: Feb 9, 2026Locations: 1
Eligibility criteria

Patients with proven solid tumors or newly diagnosed mass strongly suspected to... [+2]

Patient has contraindications for MRI or PET/MR. This includes patients with car... [+3]

Status: Recruiting

Application of Topical Oxygen Therapy Around Customized Healing Collar

The preservation and enhancement of peri-implant soft tissues are essential for the long-term success and esthetic integration of dental implants. Customized healing abutments have been introduced to support individualized soft tissue shaping; however, optimizing soft tissue healing around implants remains a clinical challenge. Oxygen plays a critical role in wound healing by promoting angiogenesis, fibroblast proliferation, and collagen synthesis. Topical oxygen therapy has shown promise in accelerating tissue regeneration, yet its application in oral implantology, particularly in conjunction with customized healing abutments, has not been adequately studied. This study aims to provide clinical evidence regarding the effectiveness of topical oxygen therapy in improving linear and volumetric soft tissue changes around dental implants. The findings may guide clinicians in refining soft tissue management protocols and contribute to establishing evidence-based practices in implant dentistry.

Participants needed: 6
Trial details
Phase: Phase 4Age: 21+Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Feb 3, 2026Locations: 1
Eligibility criteria

Adults aged 21 years and above. [+4]

Individuals below 21 years old. [+5]