Solid Tumors With HRAS Alterations

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Review clinical trials related to Solid Tumors With HRAS Alterations. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

This first-in-human (FIH) dose-escalation and dose-validation/expansion study will assess KO-2806, a farnesyltransferase inhibitor (FTI), as a monotherapy and in combination, in adult patients with advanced solid tumors.

Participants needed: 300
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Kura Oncology, Inc.Updated: Jun 8, 2026Locations: 38
Eligibility criteria

At least 18 years of age. [+12]

Any use of anticancer therapy within 14 days or 5 half-lives (whichever is short... [+10]