Spinal Cord Injury at C5-C7 Level

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Review clinical trials related to Spinal Cord Injury at C5-C7 Level. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Nerve Transfer Surgery to Restore Upper-limb Function After Cervical Spinal Cord Injury

The goal of this prospective, open-label cohort study is to assess functional outcomes in individuals with cervical spinal cord injury who have undergone nerve transfer surgery to restore upper limb function. The main questions it aims to answer are: * Does nerve transfer improve hand function in individuals with cervical spinal cord injury? * What factors are associated with functional improvement following nerve transfer? Researchers will compare functional outcomes at 24 months post-surgery to 1) baseline outcomes and 2) individuals with cervical spinal cord injury who did not undergo nerve transfer. Participants who have received nerve transfer surgery as part of their regular medical care will complete functional hand tests, electrodiagnostic assessments, and questionnaires on independence and mood every 3 months for 24 months after surgery.

Participants needed: 40
Trial details
Age: 18-70Biological sex: AllType: ObservationalSponsor: University of British ColumbiaUpdated: May 29, 2026Locations: 4Duration: 2 Years
Eligibility criteria

Traumatic, motor-complete cervical SCI (AIS A or B) [+8]

Inability or unwillingness to participate in post-operative rehabilitation (in p... [+1]

Status: Recruiting

Grasp-Release Assessment of a Networked Neuroprosthesis Device

The overall objective of this trial is to characterize the safety and effectiveness of the Networked Neuroprosthesis Device - Upper Extremity (NP-UE) in individuals living with cervical SCI.

Participants needed: 13
Trial details
Age: 16+Biological sex: AllType: InterventionalSponsor: MetroHealth Medical CenterUpdated: Dec 19, 2025Locations: 1
Eligibility criteria

Male or female, age > 16 years. [+10]

Other neurological conditions (MS(multiple Sclerosis), diabetes with peripheral... [+13]

Status: Recruiting

Multi-functional Neuroprosthetic System for Restoration of Motor Function in Spinal Cord Injury

This study is to evaluate the use of a fully implanted device for providing hand function, reach, and trunk function to individuals with cervical spinal cord injury. Funding Sources: FDA OOPD NIH NINDS

Participants needed: 30
Trial details
Age: 17+Biological sex: AllType: InterventionalSponsor: Anne BrydenUpdated: Dec 19, 2025Locations: 1
Eligibility criteria

Diagnosis of cervical level spinal cord injury, either complete or incomplete; I... [+5]

Currently pregnant (neuroprosthesis implantation delayed until no longer pregnan... [+13]

Status: Recruiting

Neuromodulation With Spinal Stimulation Methods

This is a pilot research study to test the protocols needed for transcutaneous spinal electrical stimulation in persons living with spinal cord injury (SCI). Up to 24 participants will be enrolled. A variety of stimulation parameters and outcome measures will be assessed.

Participants needed: 24
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: University of ManitobaUpdated: Feb 10, 2025Locations: 2
Eligibility criteria

spinal cord injury C4 to L4 [+1]

history of seizures, head injury, concussion, unexplained loss of consciousness...