Spinal Instability of Thoracolumbar Region

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Review clinical trials related to Spinal Instability of Thoracolumbar Region. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Surgical Versus Non-Surgical Treatment of Thoracolumbar Burst Fracture

Treatment for acute traumatic thoracolumbar burst fractures differs significantly across the world in patients without neurological impairments and without damage to the posterior column of the spine. This randomized controlled, non-inferiority clinical trial's goal is to evaluate the effectiveness of surgery versus initial non-surgical treatment for patients with traumatic thoracolumbar spine burst fractures who don't have any neurological symptoms. The study's precise objectives are to: 1. evaluate the clinical outcome (Oswestry Disability Index) 2. evaluate the radiography result (restoration and maintenance of spinal alignment) 3. determine the prevalence of complications at least 24 months of follow-up of neurologically unaffected patients with acute traumatic burst fractures. Both groups will get the same therapy using standardized methods: The surgical group's entire patient population will get combined anterior-posterior (360°) spinal fusion therapy. Three-point hyperextension orthoses will be used to treat all patients in the non-surgical group for six weeks following the injury.

Participants needed: 52
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Insel Gruppe AG, University Hospital BernUpdated: May 7, 2026Locations: 2
Eligibility criteria

Age 18 - 70 years at inclusion [+2]

Injury of the posterior tension band/posterior column of the thoracolumbar spine [+9]