Spine Stereotactic Radiosurgery (sSRS)

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Review clinical trials related to Spine Stereotactic Radiosurgery (sSRS). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms. Spine SRS uses special equipment to position the participant and guide the focused beams toward the area to be treated and away from normal tissue. One of the side effects of spine SRS is the development of vertebral compression fractures, many of which are not painful. The goal of this study is to compare the effects, good and/or bad, of spine SRS given in 1 or 2 treatments. Our main goal is to find out which approach will reduce the chances of developing vertebral compression fractures.

Participants needed: 130
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Case Comprehensive Cancer CenterUpdated: Jun 5, 2026Locations: 1
Eligibility criteria

Karnofsky Performance Status (KPS) ≥ 70 [+13]

Lesions at C1-2 or S1-Coccyx. [+18]