Squamous Cell Carcinoma of Cervix

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Review clinical trials related to Squamous Cell Carcinoma of Cervix. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Intra-lesional Tumor Boost for Bulky Cervical Cancer

The goal of this clinical trial is to learn if adding a radiation boost (intra-lesional boost) works to treat patients with large-sized cervical cancer. It will also learn about the safety of this treatment. The main questions it aims to answer are: * Does the extra radiation boost effectively reduce the tumor size before the internal radiation (brachytherapy) treatment begins? * What medical problems (side effects) do participants have when receiving this treatment? Researchers will give this intra-lesional boost to all participants during their standard radiation therapy to see if it helps shrink the tumor more than usual. Participants will: * Receive radiation therapy to the pelvis with a targeted boost to the tumor for about 5 to 6 weeks * Visit the clinic daily for radiation treatment and regularly for checkups Have an MRI scan during the 4th or 5th week of treatment to measure the tumor size * Receive internal radiation therapy (brachytherapy) after finishing the external radiation * Visit the clinic for follow-up checkups and tests for up to 2 years

Participants needed: 17
Trial details
Phase: Phase 2Age: 19-80Biological sex: FemaleType: InterventionalSponsor: Seoul National University Bundang HospitalUpdated: Feb 27, 2026Locations: 1
Eligibility criteria

Patients with histologically confirmed squamous cell carcinoma of the cervix. [+4]

Diagnosis of other malignancies within 5 years prior to enrollment (Exceptions:... [+4]