Squamous Cell Carcinoma of the Oral Cavity

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Review clinical trials related to Squamous Cell Carcinoma of the Oral Cavity. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

De-Intensification of Postoperative Radiotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck

This randomized, prospective, multicenter phase II/III trial will study the reduction of radiation volume by eliminating radiotherapy (RT) to the elective neck using strictly defined surgical and radio-oncological standards to reduce radiotherapy-related long-term side effects without affecting locoregional control.

Participants needed: 508
Trial details
Phase: Phase 2, Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: University of Erlangen-Nürnberg Medical SchoolUpdated: Mar 13, 2026Locations: 1
Eligibility criteria

Histologically proven squamous cell carcinoma of the oral cavity/larynx/oro-or h... [+10]

macroscopic incomplete resection R2 [+11]

Status: Recruiting

Fluorescence-guided Surgery Using cRGD-ZW800-1 in Oral Cancer

This is a two-staged clinical trial to investigate the feasibility of intraoperative Fluorescence Imaging (FLI) to adequately assess tumor margins in patients with oral cancer using cRGD-ZW800-1.

Participants needed: 28
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Erasmus Medical CenterUpdated: Feb 26, 2025Locations: 1
Eligibility criteria

Patients with biopsy-proven squamous cell carcinoma of the oral cavity, eligible... [+3]

Previous surgery, chemotherapy or radiotherapy to the oral cavity; [+6]

Status: Recruiting

Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome

Prospective, open, non-interventional, multi-center clinical registry study with the aim to establish a comprehensive research platform reflecting the real-world treatment landscape for recurrent/metastatic head and neck tumor patients.

Participants needed: 120
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: AIO-Studien-gGmbHUpdated: Nov 13, 2024Locations: 2Duration: 36 Months
Eligibility criteria

Age ≥ 18 years [+4]

Status: Not yet recruiting

CHG0521 Oral Coating in Patients with Solid Tissue Tumor/Recurrent/Metastatic TSCC

This is a prospective single-arm loading test study of CHG0521 oral coating in patients with solid tissue tumor/recurrent/metastatic TSCC

Participants needed: 30
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Guangzhou University of Traditional Chinese MedicineUpdated: Sep 23, 2024
Eligibility criteria

1. Age range: 18-80 years, encompassing both males and females. 2. Confirmation...

1. Patients with tongue squamous cell carcinoma who have undergone tumor resecti...