Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v8

1

Review clinical trials related to Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v8. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

This study is being done to assess mogamulizumab-associated rash in patients diagnosed with mycosis fungoides or sezary syndrome and treated with standard of care mogamulizumab. One of the most common side effects of mogamulizumab is a rash, currently named mogamulizumab-associated rash (MAR) which can look like MF or SS. However, mogamulizumab-associated rash (MAR) does not indicate failure of mogamulizumab, and may be a sign that the drug is working. If not properly evaluated, mogamulizumab-associated rash (MAR) could be misinterpreted as worsening of mycosis fungoides/sezary syndrome, which could lead doctors to recommend stopping mogamulizumab treatment early. The information learned by doing this research study may help tell the difference between mogamulizumab-associated rash (MAR) (sometimes also called "drug eruption") and worsening of the disease. It may also help to uncover information about the cause of mogamulizumab-associated rash (MAR).

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: City of Hope Medical CenterUpdated: Sep 9, 2025Locations: 10
Eligibility criteria

* Adult patients (>= 18 years of age) diagnosed with relapsed/refractory Mycosis... [+3]

* Other concomitant systemic and skin directed Cutaneous T-cell Lymphoma (CTCL)... [+1]