Sternotomy Closure,Open Heart Surgery

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Review clinical trials related to Sternotomy Closure,Open Heart Surgery. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Adjustable Carbon Fiber Sternal Plates for Sternotomy Closure

The goal of this clinical trial is to learn if a new medical device (SC03 plates) to close the sternum after a sternotomy in patients that have been operated of a cardiac surgery, is safe and effective. The main question it aims to answer is: Do patients that have the sternum closed with the SC03 plates present a stable sternum one month after surgery? Researchers will compare the SC03 plates with stainless steel wires (current standard of care to close the sternum). Participants will: * be implanted with the SC03 or stainless steel wires. * visit the clinic one month and six months after surgery * Keep a diary of their symptoms and analgesia use

Participants needed: 190
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: NEOS SurgeryUpdated: Jan 26, 2026
Eligibility criteria

Patient ≥ 18 years old. [+3]

Patient with sternal anomalies, such as bone tumours located in the sternum. [+14]

Status: Not yet recruiting

Botulinum Toxin Injection After Sternotomies to Improve Scar Aspect and Impact

Sternotomy scars, which are localized in a high-tension area are often dystrophic, hypertrophic or keloidal, and can be difficult to accept to patients who already endured a heavy intervention with high psychologic impact. The investigators wish to evaluate immediate post-surgical injection of botulinum toxin to improve scar aspect and impact. A randomized, placebo-controlled, split-scar clinical trial will determine the improvement of scar aspects assessed by standardized scores (SBSES, POSAS), patient satisfaction and tolerance.

Participants needed: 50
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: University Hospital, BordeauxUpdated: Jun 10, 2025Locations: 1
Eligibility criteria

Patient aged 18 years or older [+4]

Known allergy to botulinum toxin type A or any excipient in BOTOX® (human albumi... [+5]