Status: Not yet recruiting
Isosorbide Mononitrate and Butylphthalide to Reduce the Risk of Disability in Patients With Acute Lacunar Stroke (IMPACT)
The goal of this multicenter, double-blind, 2×2 factorial randomized controlled trial is to evaluate the efficacy and safety of isosorbide mononitrate, butylphthalide, and their combination in reducing disability in patients with acute lacunar stroke.
Participants needed: 3,156
Trial details
Phase: Phase 3Age: 30+Biological sex: AllType: InterventionalSponsor: Beijing Tiantan HospitalUpdated: Nov 26, 2025
Eligibility criteria
Age ≥ 30 years; [+8]
Ischemic stroke of large artery atherosclerosis, cardioembolism, or other etiolo... [+18]