Suicide Threat

4

Review clinical trials related to Suicide Threat. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Written Exposure Therapy for Suicide Prevention

Military service members admitted to inpatient psychiatry for self-injurious thoughts and behaviors (SITBs) represent an at-risk group for continued SITBs and rehospitalizations in the post-discharge period. However, there is an absence of evidence-based interventions designed to be delivered on inpatient psychiatric units to reduce the risk of post-discharge SITBs. To address this gap, the investigator's research group developed Written Exposure Therapy for Suicide Prevention (WET-SP), a brief, scalable, suicide-specific psychotherapy based on the written disclosure paradigm. Written disclosure, in which an individual writes about a personally stressful experience and the related thoughts and feelings, yields improvements across physical and psychiatric domains. Pilot data suggest that written exposure also yields reductions in SITBs. Yet, no study has adapted the written exposure paradigm specifically to target the amelioration of distress associated with suicidal crises and examined whether implementing WET-SP reduces the risk of subsequent SITBs and suicide-related hospitalizations. The primary objective of this randomized controlled trial (RCT) is to evaluate the efficacy of WET-SP, in reducing the incidence and severity of SITBs in active duty military service members following a psychiatric hospitalization due to suicidal ideation, suicide plans, or a suicide attempt. Secondary objectives are to evaluate a potential mechanism of change (i.e., decreases in thwarted belongingness \[cf. social disconnectedness\]) and moderator of outcomes (i.e., arc of narrative \[cf. linguistical parameters of the written narratives generated during treatment\]). Participants randomized to WET-SP + TAU will receive five sessions of WET-SP delivered by the study team during their psychiatric hospitalization plus treatment-as-usual (TAU). Participants randomized to TAU will receive daily contact and patient-centered care delivered by the acute psychiatric inpatient unit provider team (e.g., psychiatrists, therapists, case managers). TAU includes psychiatric assessment, initial stabilization, nurse case management, medication management, treatment of medical comorbidities, group and individual therapy, and discharge planning. Outcome assessments will be administered at pretreatment, posttreatment, and 10-, 20-, and 30-week follow-ups.

Participants needed: 160
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Boston UniversityUpdated: May 29, 2026Locations: 1
Eligibility criteria

Current active duty military service member, veteran, and beneficiaries [+3]

Active psychosis as the priority of care for hospitalization [+2]

Status: Recruiting

Advancing Suicide Intervention Strategies for Teens During High Risk Periods

To inform the effective management of adolescent suicide risk by evaluating promising treatments and developing the evidence-base for interventions that are well suited for widespread adoption, sustained quality, and impact.

Participants needed: 306
Trial details
Age: 11-17Biological sex: AllType: InterventionalSponsor: Seattle Children's HospitalUpdated: Nov 14, 2025Locations: 2
Eligibility criteria

Provision of signed and dated informed consent form [+3]

Presence of psychosis, intellectual disability, autism spectrum disorder, eating... [+1]

Status: Recruiting

Intensive Crisis Intervention

The study's purpose is to improve the clinical management of severe crises experienced by youth with psychiatric disorders by examining a brief, evidence-based alternative to inpatient psychiatric care.

Participants needed: 213
Trial details
Age: 12-17Biological sex: AllType: InterventionalSponsor: Jennifer HughesUpdated: Aug 7, 2025Locations: 1
Eligibility criteria

Youth between the ages of 12 years 0 months and 17 years 6 months at time of con... [+6]

Participants who are unable to understand study procedures (e.g., intellectual d... [+1]

Status: Recruiting

Psychoeducational Course for Suicide Prevention

The plan is to include patients with a history of increased risk of suicide. In the aftermath of an episode of imminent suicide risk, patients will receive a psychoeducational course that entails information on different aspects of suicide-related topics, identifying triggers and detecting early warning signals for increased suicide risk. The course culminates in working on completing a individual safety plan to prevent an future increase in suicide risk. The course will incorporate both patients and their next of kin. The psychoeducational course will be compared to a control group where the patients receive one individual session with focus on a safety plan to evaluate the intervention. Both groups will receive treatment as usual (TAU) during both the acute phase and follow-up. The study will be conducted as a randomized controlled trial.

Participants needed: 80
Trial details
Age: 18-99Biological sex: AllType: InterventionalSponsor: St. Olavs HospitalUpdated: Feb 26, 2025Locations: 2
Eligibility criteria

Patients with a suicide attempt, suicidal behavior, or risk of suicidal behavior... [+1]

Not being sufficiently fluent in Norwegian to provide informed consent, valid re... [+5]