T-cell Acute Lymphoblastic Leukemia/Lymphoma

2

Review clinical trials related to T-cell Acute Lymphoblastic Leukemia/Lymphoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Anti-CD7 CAR-T Cells in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia or Lymphoma

This will be a Phase 1, open-label study to evaluate the safety and efficacy of BEAM-201 in patients with R/R T-ALL or T-LLy. BEAM-201 is an allogeneic anti-CD7 CART therapy.

Participants needed: 33
Trial details
Phase: Phase 1Age: 0-29Biological sex: AllType: InterventionalSponsor: Stephan Grupp MD PhDUpdated: Dec 26, 2025Locations: 1
Eligibility criteria

Patients (ages ≥ 18 years) or parent/legal guardians (for patients ages < 18 yea... [+19]

Active hepatitis B or active hepatitis C [+18]

Status: Recruiting

Clinical Study of Senl-T7 CAR T Cells in the Treatment of Relapsed and Refractory CD7+ Acute T-ALL/T-LBL

This is an open, prospective, dose-escalation clinical study to evaluate the safety and efficacy of Senl-T7 in patients with relapsed or refractory CD7+ acute T lymphoblastic leukemia or T lymphoblastic lymphoma.Meanwhile, PK/PD indexes of Senl-T7 were collected.

Participants needed: 100
Trial details
Age: 2-70Biological sex: AllType: InterventionalSponsor: Hebei Senlang Biotechnology Inc., Ltd.Updated: Nov 25, 2022Locations: 1
Eligibility criteria

Diagnosis of relapsed/refractory T-cell lymphoblastic leukemia or T-cell lymphob... [+9]

Any of the following cardiac criteria: Atrial fibrillation/flutter; Myocardial i... [+13]