T Cell Receptor Alpha/Beta Depletion

1

Review clinical trials related to T Cell Receptor Alpha/Beta Depletion. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders

This is a phase II trial of T cell receptor alpha/beta depletion (α/β TCD) peripheral blood stem cell (PBSC) transplantation in patients with inherited bone marrow failure (BMF) disorders to eliminate the need for routine graft-versus-host disease (GVHD) immune suppression leading to earlier immune recovery and potentially a reduction in the risk of severe infections after transplantation.

Participants needed: 48
Trial details
Phase: Phase 2Age: Up to 65Biological sex: AllType: InterventionalSponsor: Masonic Cancer Center, University of MinnesotaUpdated: Jan 30, 2026Locations: 1
Eligibility criteria

Diagnosis of Fanconi anemia [+14]

Pregnant or breastfeeding as the treatment used in this study are Pregnancy Cate... [+15]