T Cell Therapy

2

Review clinical trials related to T Cell Therapy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

RE002 T Cell Injection for the Treatment of KRAS G12D Mutated Solid Tumors

At present, there is an urgent need for new drugs for KRAS mutant tumors in clinic. Preclinical studies support the specificity, safety and anti-tumor activity of RE002. Previous similar studies suggest the feasibility of TCR-T treatment, and measures have been taken to ensure the safe administration of RE002 and the close monitoring and management of adverse events. To sum up, RE002 has controllable safety and anti-tumor activity on KRAS mutant solid tumor, which can be preliminarily studied to provide support for clinical research of patients with advanced solid tumor.

Participants needed: 30
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Henan Cancer HospitalUpdated: Dec 16, 2025Locations: 1
Eligibility criteria

Subjects voluntarily participate in the study and sign informed consent; [+20]

Those who have received major surgery, conventional chemotherapy, large-area rad... [+23]

Status: Not yet recruiting

RE001 T Cell Injection for the Treatment of KRAS G12V Mutated Solid Tumors

At present, there is an urgent need for new drugs for kirsten rat sarcoma viral oncogene (KRAS) mutant tumors in clinic. Preclinical studies support the specificity, safety and anti-tumor activity of RE001. Previous similar studies suggest the feasibility of T cell receptor engineered T cell therapy (TCR-T) treatment, and measures have been taken to ensure the safe administration of RE001 and the close monitoring and management of adverse events. To sum up, RE001 has controllable safety and anti-tumor activity on KRAS mutant solid tumor, which can be preliminarily studied to provide support for clinical research of patients with advanced solid tumor.

Participants needed: 30
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Henan Cancer HospitalUpdated: Aug 9, 2024Locations: 1
Eligibility criteria

Subjects voluntarily participate in the study and sign informed consent; [+20]

Those who have received major surgery, conventional chemotherapy, large-area rad... [+23]