Tennis Elbow

12

Review clinical trials related to Tennis Elbow. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE)

This study at Hashemite University looks at how people with and without tennis elbow (AKA lateral elbow tendinopathy) feel pressure pain and how their bodies briefly "turn down" pain after a cold stimulus. Participants complete brief questionnaires (basic demographics without names, a tennis-elbow symptom form, and a physical-activity form) and then have their pressure-pain threshold (PPT) tested with a handheld device that slowly increases pressure on standard spots near the elbow and wrist; they say when it first becomes painful. To test the body's built-in anti-pain system (conditioned pain modulation, CPM), one hand is placed in ice water (the cold-pressor task) and PPT is measured again at set times (before, during, and after the cold stimulus) to see how much pain sensitivity changes and how long that change lasts. Both PPT reliability and CPM after effect are measured in this study. The study findings may help improve future assessment and treatment of musculoskeletal pain conditions.

Participants needed: 38
Trial details
Age: Up to 60Biological sex: AllType: InterventionalSponsor: The Hashemite UniversityUpdated: Jun 26, 2026Locations: 1
Eligibility criteria

Palpation of the lateral epicondyle [+5]

History of chronic pain conditions (e.g. fibromyalgia, irritable bowel [+6]

Status: Not yet recruiting

Arthroscopic Versus Open Management of Lateral Epicondylitis Elbow (Randomized Control Trial)

Arthroscopic Versus Open management of lateral epicondylitis elbow (Randomized Control Trial)

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Assiut UniversityUpdated: Jun 15, 2026
Eligibility criteria

tennis elbow not responding to conservative measures (more than 6 months) adult...

Degenerative changes of the elbow (as inflammatory diseases) Previously operated...

Status: Recruiting

Wrist Heavy Slow Resistance and Shoulder Stabilization Exercises on Pain, Grip Strength and Functional Ability in Lateral Epicondylitis

The study will compare the shoulder and wrist treatment approaches to determine their effect on elbow. Thirty-two medically stable participants with active shoulder and wrist movements will be enrolled into two groups. Both groups will receive structured training for six weeks. Outcomes will be measured using standardized assessment tools. The aim is to identify the more effective strategy for improving upper limb kinetic chain which is affected by lateral epicondylitis

Participants needed: 32
Trial details
Age: 30-50Biological sex: AllType: InterventionalSponsor: University of FaisalabadUpdated: May 8, 2026Locations: 1
Eligibility criteria

Both genders will be involved with ages 30-50. Patients who have had pain for th...

Those who will have pain on the lateral aspect of the elbow for 6 months or more...

Status: Recruiting

Comparative Effects of Shockwave Therapy and Eccentric Exercises in Patients With Lateral Epicondylitis

The goal of this randomized controlled trial is to compare the effects of shockwave therapy and eccentric exercises on pain, functional ability, quality of life, grip strength and range of motion in patients with lateral epicondylitis. Participants will be randomly assigned to either Group A (Shockwave therapy) or Group B (Eccentric Exercises) using a computer-generated random number tables method. The intervention will be provided over five weeks, with three sessions per week (total of 15 sessions): Group A (Shockwave therapy): Participants will receive shockwave therapy, for 5 min with energy level 7.0 m J and frequency 6 Hz. Group B (Eccentric Exercises): Participants will receive eccentric exercises, repeating each 10 repetitions 3 sets per session with a 1 min rest between each of them. Outcomes will be assessed at baseline, week 0 and week 5 to evaluate which exercise program is more effective in reducing symptoms and improving functional outcomes.

Participants needed: 50
Trial details
Age: 20-50Biological sex: AllType: InterventionalSponsor: Ibadat International University, IslamabadUpdated: Apr 13, 2026Locations: 1
Eligibility criteria

Patients diagnosed with Lateral epicondylitis [+3]

Patients with recent trauma (fractures, injury etc.) [+3]

Status: Recruiting

Comparison of the Efficacy of Mesotherapy and Extracorporeal Shock Wave Therapy in Patients With Lateral Epicondylitis

The goal of this clinical trial is to investigate the efficacy of mesotherapy in patients with lateral epicondylitis and to determine whether it is as effective as extracorporeal shock wave therapy (ESWT). Is mesotherapy an effective method in patients with lateral epicondylitis? Researchers will compare Mesotherapy to extracorporeal shock wave therapy (ESWT) in patient with Lateral epicondylitis. Patients will be randomly assigned to either the Mesotherapy group or the ESWT group using a closed envelope method. * Group 1 (Mesotherapy group): Patients will receive a total of 5 sessions of mesotherapy, with one session every 7 days. * Group 2 (ESWT group): Patients will receive a total of 5 sessions of Extracorporeal Shock Wave Therapy (ESWT), with one session every 7 days. Patients will be assessed at three time points: before treatment, 30 minutes after the completion of the treatment, and 12 weeks after the completion of the treatment

Participants needed: 50
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Haydarpasa Numune Training and Research HospitalUpdated: Feb 18, 2026Locations: 1
Eligibility criteria

Aged between 18 and 65 years [+3]

Receiving an interventional injection in the elbow region within the last 3 mont... [+12]

Status: Recruiting

High and Low Dose High-intensity Laser Therapy Lateral Epicondylitis

High-intensity laser therapy has gained increasing attention in recent years as a therapeutic modality. It is a non-invasive treatment that can reduce pain, increase local blood circulation, and promote tissue repair. The higher energy output of high-intensity laser therapy also have deeper tissue penetration. Several studies have investigated the effects of high-intensity laser therapy on lateral epicondylitis, and the existing literature indicates that, compared with other treatment modalities, high-intensity laser therapy is more effective in improving pain and quality of life in patients with lateral epicondylitis. However, the dosage, duration, and treatment frequency applied in previous studies vary considerably. The therapeutic effects of high-intensity laser therapy may therefore be influenced by treatment dosage. Consequently, the purpose of this study is to compare the effects of two different dosages of high-intensity laser therapy on patients with lateral epicondylitis.

Participants needed: 45
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Kaohsiung Medical University Chung-Ho Memorial HospitalUpdated: Jan 21, 2026Locations: 1
Eligibility criteria

Patients diagnosed with lateral epicondylitis by physician [+2]

Patients who have received treatments other than standard treatment to the affec... [+8]

Status: Recruiting

Effect of Scapular Stabilization Exercises and ESWT in Patients With Lateral Epicondylitis

We aim to investigate the effects of adding scapular stabilization exercises to the extracorporeal shock wave therapy (ESWT) protocol in the treatment of lateral epicondylitis on pain, muscle strength, functional status, and quality of life.

Participants needed: 48
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Saglik Bilimleri UniversitesiUpdated: Dec 4, 2025Locations: 1
Eligibility criteria

Aged between 18 and 65 years. [+3]

• Individuals with serious systemic or cardiovascular diseases that contraindica... [+11]

Status: Recruiting

Leukocyte-rich PRP or Leukocyte-free PRP vs Placebo in the Treatment of Epicondylitis

The EPIC-PRP study is a double-blind randomized controlled clinical trial with 1:1:1 allocation.The objective of the study is to evaluate by means of a randomized controlled, double-blind clinical trial the clinical outcomes of echo-guided injection of PRP with or without leukocytes compared with echo-guided injection of saline for minimally invasive treatment of patients with epicondylitis resistant to conservative therapy. It will be the aim of the study to evaluate the efficacy and safety of the injection procedures by revealing the improvement and incidence of adverse events following treatment

Participants needed: 240
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Istituto Ortopedico RizzoliUpdated: Sep 29, 2025Locations: 1
Eligibility criteria

Patients with clinical picture of epicondylitis; [+11]

Patients undergoing previous surgical treatment on the epicondylar tendons; [+13]

Status: Recruiting

Efficacy Bioinductive Implant for Tennis Elbow (Lateral Epicondylitis)

The investigators are testing the efficacy of a new, FDA-approved bioinductive patch in lateral epicondylitis (tennis elbow) patients. A bioinductive patch is an implant that may foster tendon regrowth and healing following surgery. Patients will be randomize into one of two groups: control and investigational. Patients in the "control group" will receive the normal surgery for patients who do not respond to physical therapy, lifestyle changes, and anti-inflammatory treatment. Patients in the "experimental group" will receive the same surgical treatment, with the addition of the bioinductive patch. This patch will be implanted during surgery. Then, using a combination of ultrasound studies and other measures, the investigators will assess how well the patch works compared to surgery alone.

Participants needed: 40
Trial details
Phase: Phase 4Age: 18+Biological sex: MaleType: InterventionalSponsor: Henry Ford Health SystemUpdated: Mar 12, 2025Locations: 1
Eligibility criteria

Diagnosis of lateral epicondylitis (tennis elbow) that has failed conservative t...

Previous surgery on the currently-affected elbow.

Status: Not yet recruiting

Comparative Effects of Sustained Stretch and Mobilization With Movement in Patient With Tennis Elbow

Tennis elbow, clinically known as lateral epicondylitis, is a prevalent musculoskeletal issue marked by pain and tenderness on the outer part of the elbow. It primarily affects the extensor tendon at the lateral epicondyle and is commonly linked to repetitive arm movements and overuse. Various treatment options are available for this condition, with two notable methods being sustained stretching and Mobilization with Movement (MWM). Sustained stretching involves holding the affected muscles and tendons in an extended position for a prolonged time to ease muscle tightness and enhance flexibility. Conversely, MWM integrates specific joint movements with the active involvement of the patient to improve joint mobility and reduce pain. Muscle strength plays a crucial role in the overall function of the upper limb, and enhancing this can positively affect daily activities. Furthermore, functional disability indicates how tennis elbow impacts a person's capacity to carry out everyday tasks.

Participants needed: 30
Trial details
Age: 20-45Biological sex: AllType: InterventionalSponsor: Riphah International UniversityUpdated: Nov 5, 2024Locations: 1
Eligibility criteria

Both males and females are affected. diagnosed with tennis elbow, characterized... [+3]

Presence of nerve injuries or neuropathies in the arm or hand. [+4]

Status: Recruiting

Comparing Injection Treatments for Tennis Elbow

Tennis elbow is one of the most common musculoskeletal problems affecting the arm and is thought to be mainly due to overuse of the muscles that extend the wrist. The pain arises from the lateral epicondyle of the humerus, where the tendons of the wrist extensor muscles attach. There are many treatment options available for tennis elbow including oral medication, physiotherapy and injection therapy. Surgical options are reserved for those who fail to respond to more conservative treatments. Physiotherapy is a widely used, non-invasive treatment option for the management of tennis elbow. Research has shown that in the longer term, physiotherapy is superior to corticosteroid injection in the treatment of tennis elbow and a meta-analysis of published research concluded that Platelet Rich Plasma injection and Hyaluronic Acid injection are superior to corticosteroid for long term pain relief in tennis elbow. At present there is not enough evidence to indicate what the 'Gold Standard' treatment for tennis elbow is, and more research is therefore needed to help guide decision-making. The aim of this study is therefore to examine the effects of injection therapy in addition to physiotherapy treatment, in comparison to physiotherapy and a control injection on pain and function in patients with tennis elbow. All participants in this study will undergo a structured, specifically designed, class-based physiotherapy intervention, in addition to being randomly allocated to receive one of the following three types of injection: (a) a control injection whereby a needle is inserted into the skin but no therapeutic substance is injection, (b) a single therapeutic injection of platelet-rich plasm or (c) a single therapeutic injection of hyaluronic acid. Baseline data will be collected at the time of recruitment and participants will be followed up at 3 months and 12 months post treatment. Outcomes will be assessed using various patient-reported outcome measures in addition to clinical examination. The primary outcome for this study is the improvement in the quick DASH score at 12 months post-treatment compared to baseline.

Participants needed: 123
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Wrightington, Wigan and Leigh NHS Foundation TrustUpdated: Aug 6, 2024Locations: 1
Eligibility criteria

Absence of tenderness at the lateral epicondyle. [+10]

Status: Recruiting

The Effect of Blood Flow Restriction Training on Tennis Elbow

The goal of this randomized controlled clinical trial is to investigate the effects of blood flow restriction training on the parameters surrounding tennis elbow afflicted patients including pain, disability, and grip strength. The main question this study aims to answer is: 1- Does blood flow restriction training offer significantly better effects on pain, disability, and grip strength when compared to conventional strength training without blood flow restriction in patients afflicted with tennis elbow? Research will compare two groups with tennis elbow where both will perform the same rehabilitation program consisting of conventional physical therapy for tennis elbow as well as a strength training program with the only difference being that one group will undergo blood flow restriction training while the other will not.

Participants needed: 25
Trial details
Age: 18-28Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Jul 8, 2024Locations: 1
Eligibility criteria

Patients that were included in this study were diagnosed with lateral epicondyli... [+4]

Patients with chronic diabetes. [+5]