Tension Headache

3

Review clinical trials related to Tension Headache. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Effect of Laser Acupuncture on Tension Headache in Post-Pubertal Females

This study will be carried out to evaluate the effect of laser acupuncture on tension headache in post-pubertal females.

Participants needed: 60
Trial details
Age: 15-18Biological sex: FemaleType: InterventionalSponsor: Cairo UniversityUpdated: Feb 18, 2026Locations: 1
Eligibility criteria

Their age will be ranged from 15 to 18 years. [+4]

Patients with other causes of headache. [+4]

Status: Recruiting

nVNS for the Prevention and Treatment of Primary Headache

This study is a single-center, single-arm study. All subjects will receive the same treatment. Children and adolescents (7-20 years old) with migraine who met the inclusion criteria will be enrolled as subjects in the experimental group, and the changes in headache scores before and after the intervention will be compared. The intervention method is as follows: ictal intervention, in which subjects will be evaluated for headache improvement after a short intervention during an acute exacerbation. By wearing a vagus stimulator, the stimulating electrode will be located in the concha region rich in vagus nerve fiber endings, and the appropriate stimulation intensity will be adjusted for stimulation. Therefore, this study will verify the effect of nVNS on the acute treatment of primary headache in children and adolescents. Based on the electrocardiogram and electromyography indicators during the intervention process of nVNS, an objective evaluation system for the improvement of headache by nVNS is established, and the role of stimulation parameters on the effect is further explored to realize the optimization of parameters.

Participants needed: 15
Trial details
Age: 7-20Biological sex: AllType: InterventionalSponsor: Nanfang Hospital, Southern Medical UniversityUpdated: Aug 12, 2025Locations: 1
Eligibility criteria

Patients with migraine, cluster headache and tension-type headache were diagnose... [+4]

History of secondary headache, aneurysm, intracranial hemorrhage, brain tumor, s... [+10]

Status: Not yet recruiting

0.5% Bupivacaine Lower Cervical Intramuscular Injection vs IV Medications for Headache Treatment

Headache is a frequent chief complaint among patients presenting to the Emergency Department (ED), accounting for 2.1 million visits annually in the United States. Often, individuals resort to ED care only after over-the-counter or home remedies have failed, leading to the predominant use of intravenous (IV) medications in the ED, including NSAIDs, triptans, neuroleptics, antiepileptics, and dopaminergic antagonists. Unfortunately, these pharmacologic treatments frequently induce side effects such as cognitive impairment, extrapyramidal reactions, and the potential for medication dependency. In the ED, patients frequently require concurrent administration of multiple systemic medications to achieve satisfactory pain relief, thereby elevating the risk associated with medication use. Despite these medication regimens, a significant portion of patients continue to experience inadequate pain relief. Consequently, the search for an optimal headache therapy-characterized by rapid and effective pain relief, long lasting results, minimal side effects, and allows for rapid ED patient turnover-continues to be a popular area of research in emergency medicine. The investigators plan to evaluate the use of 0.5% bupivacaine cervical IM injection at the c6-7 location for the treatment of non traumatic headaches using a non-inferiority design, randomized, prospective, open-label, controlled trial comparing it to physicians choice of intravenous medications in treatment of headache in the Emergency Department at North Florida Hospital.

Participants needed: 100
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: HCA Florida North Florida HospitalUpdated: Apr 24, 2025Locations: 1
Eligibility criteria

Patient has to be able to provide own consent [+2]

traumatic headache [+9]