Thin Peri-implant Mucosal Phenotype

1

Review clinical trials related to Thin Peri-implant Mucosal Phenotype. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Peri-implant Soft Tissue Augmentation Using Microneedling With i-PRF vs. Connective Tissue Graft

This randomized controlled clinical trial aims to evaluate a minimally invasive technique for peri-implant soft tissue augmentation using microneedling combined with injectable platelet-rich fibrin (i-PRF) compared with the current gold-standard connective tissue graft (CTG). Patients with thin peri-implant soft tissue requiring implant second-stage surgery in the esthetic zone will be randomly assigned to receive either CTG harvested from the palate or a series of microneedling and i-PRF treatments. Clinical outcomes including mucosal thickness, keratinized tissue width, peri-implant health parameters, volumetric soft tissue changes, esthetic outcomes, and patient-reported measures of pain and satisfaction will be evaluated during follow-up. The study aims to determine whether microneedling with i-PRF can provide comparable soft tissue augmentation while reducing patient morbidity associated with connective tissue graft harvesting.

Participants needed: 24
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Beirut Arab UniversityUpdated: Jun 25, 2026Locations: 1
Eligibility criteria

Systemically healthy adults (Between 18 and 65) with one or more dental implants... [+4]

Heavy smokers (≥10 cig/day); light smokers only if reduced. [+7]