Thoracic Outlet Syndrome

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Review clinical trials related to Thoracic Outlet Syndrome. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Motivational Interviewing in Thoracic Outlet Syndrome

The goal of this clinical trial is to learn if motivational interviewing (MI) works to improve symptoms in people with thoracic outlet syndrome (TOS). TOS is a condition that causes long-term pain, numbness, and weakness in the arm and shoulder area. The main questions it aims to answer are: * Does MI lower pain and improve arm function in people with TOS? * Does psychological resilience predict treatment outcomes in people with TOS? Researchers will compare participants who receive MI sessions plus a home exercise program to those who receive a home exercise program alone. Participants will be randomly assigned to one of the two groups. Participants will: * Follow a home exercise program for 6 weeks * Some participants will also attend up to 4 motivational interviewing sessions * Complete questionnaires about pain, function, sleep, anxiety, and depression at the start and end of the 6-week program

Participants needed: 70
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Hacettepe UniversityUpdated: Jun 25, 2026Locations: 1
Eligibility criteria

Diagnosis of thoracic outlet syndrome [+3]

Accompanying pathologies (cervical disc problems, fibromyalgia, rotator cuff pro... [+1]

Status: Not yet recruiting

Effect of Low-Power Laser Therapy on Pain and Functional Outcomes in Patients With Thoracic Outlet Syndrome

The purpose of this study is to evaluate the effect of low-power laser therapy on pain intensity and functional outcomes in patients diagnosed with Thoracic Outlet Syndrome (TOS). Participants will be randomly assigned to either receive the active laser therapy combined with a physical therapy program or a control group. The study aims to determine if adding laser therapy provides better relief and improves daily physical functions compared to conventional treatment alone.

Participants needed: 40
Trial details
Age: 30-50Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Apr 17, 2026
Eligibility criteria

Age [+5]

History of cervical disc herniation or cervical radiculopathy. [+4]

Status: Recruiting

Vascular Lab Resource (VLR) Biorepository

This is a study of biomarkers obtained from prospectively collected subject samples and their correlation with cardiovascular and metabolic diseases. The purpose of this initiative is to develop an enduring tool to allow for collaborative research between clinicians at Cleveland Clinic Main Campus and basic scientists at the Lerner Research Institute. This collaboration will allow resources to be available to clinical and basic researchers alike. This tool will enable research of vascular disease in the Vascular Lab and will leverage this valuable asset to the fullest extent to allow for interdepartmental collaboration.

Participants needed: 500
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: The Cleveland ClinicUpdated: Dec 19, 2025Locations: 1
Eligibility criteria

18 years or older [+2]

Known life expectancy of ≤ 6 months at the time of enrollment [+2]

Status: Recruiting

Dysfunctional Breathing in Individuals With Thoracic Outlet Syndrome

The aim of this observational study was to learn about the characteristics of dysfunctional breathing in individuals with thoracic outlet syndrome. The main question to be answered is: Is there a dysfunctional breathing pattern in individuals with Thoracic outlet syndrome? These features will be compared with a healthy control group to evaluate the association of Thoracic outlet syndrome with dysfunctional breathing

Participants needed: 54
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Hacettepe UniversityUpdated: May 28, 2025Locations: 1
Eligibility criteria

To agree to participate in the study, [+3]

Patients with a history of spinal or thoracic surgery for TOS or any other reaso... [+5]