Thoracolumbosacral Orthosis

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Review clinical trials related to Thoracolumbosacral Orthosis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Post-Operative Thoracolumosacral Orthosis for PJK

Proximal junctional kyphosis (PJK) is a common post-operative radiographic finding after surgery for adult spinal deformity (ASD) patients. Although the clinical relevance of isolated PJK is unclear, PJK can progress to symptomatic proximal junctional failures which requires a large revision surgery. Currently, post-operative bracing with a thoracolumbosacral orthosis (TLSO) is common practice after spinal deformity surgery, however the efficacy of this in preventing PJK is unknown. This multi-center randomized control trial identified 84 patients undergoing thoracolumbosacral fusion for ASD and plans to study the efficacy of a novel post-operative TLSO in preventing the development of PJK as defined by the proximal junctional angle on 6-month post-operative X-rays.

Participants needed: 84
Trial details
Phase: Phase 4Age: 30-75Biological sex: AllType: InterventionalSponsor: Hospital for Special Surgery, New YorkUpdated: Feb 13, 2026Locations: 6
Eligibility criteria

30-75-years-old [+1]

Osteoporosis (defined as a T-score <-2.5 at the time of surgery) [+5]