Thromboembolus

1

Review clinical trials related to Thromboembolus. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Comparative Outcomes of PCC and Recombinant Activated Factor VIIa in Trauma-Associated Massive Transfusion

This study aims to compare the incidence of thromboembolic complications among trauma patients receiving PCC, rFVIIa, both agents, or neither during massive transfusion. Secondary objectives include comparing mortality, transfusion requirements, intensive care unit (ICU) and hospital length of stay, ventilator-free days, and the incidence of transfusion-associated adverse events such as transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory overload (TACO). Subgroup analyses will evaluate outcomes in patients with and without laboratory-confirmed TIC (INR \>1.2).

Participants needed: 4
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Zeliha AlicikusUpdated: Apr 14, 2026Locations: 2
Eligibility criteria

Adults ≥18 years [+2]

Traumatic cardiac injury [+4]