Health Trials

TNF

2

Review clinical trials related to TNF. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Apremilast and Adalimumab in Psoriatic Arthritis Patients

The aim of this work is to compare the efficacy of Apremilast combined with Methotrexate versus Adalimumab combined with Methotrexate

Participants needed: 60
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Tanta UniversityUpdated: Feb 10, 2026Locations: 1
Eligibility criteria

This study will include 60 adult Psoriatic arthritis patients >18 years old, ful... [+1]

Patients who received previous biologic agents or Janus kinase inhibitors. [+5]

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Status: Not yet recruiting

A Two-blinded, Multicentre, Phase II/III RCT of Concurrent Chemo-radiotherapy Combined or Not Combined With TNF as the Therapy for LA-NPC

Based on the application prospect of rmh-TNF combined with chemotherapy in the treatment of solid tumors. In this study, cisplatin combined with low dose 5-FU was proposed to enhance the immune function of 5-FU. Tianenfu is a novel recombinant modified human tumor necrosis with high activity and low toxicity. The fact that RMH-TNF has the potential of better in vivo efficacy and clinical antitumor effect. Therefore, the study was designed to investigate the treatment of concurrent chemoradiotherapy combined with TNF versus concurrent chemoradiotherapy combined with placebo for the efficacy and safety of advanced nasopharyngeal carcinoma.

Participants needed: 172
Trial details
Phase: Phase 2, Phase 3Age: 18-60Biological sex: AllType: InterventionalSponsor: Sun Yat-sen UniversityUpdated: Jun 27, 2022
Eligibility criteria

≥18 years old and ≤60 years old; [+13]

Have a history of allergy to 5-FU, cisplatin and tumor necrosis factor; [+11]

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