Tonsillar Hypertrophy

6

Review clinical trials related to Tonsillar Hypertrophy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Full-wrap Versus Conventional Suspension for Reducing Soft Palate Injury Rate

This study aims to evaluate whether the use of full-wrap suspension, compared with the traditional double-strap suspension, can effectively reduce the risk of intraoperative and postoperative soft palate injury in transoral/transnasal pharyngeal surgery. Through a prospective, multicenter, randomized controlled design, this study will provide evidence-based support for the clinical promotion and standardized application of full-wrap suspension.

Participants needed: 138
Trial details
Age: 2-70Biological sex: AllType: InterventionalSponsor: Sun Yat-sen UniversityUpdated: May 8, 2026Locations: 1
Eligibility criteria

Voluntarily sign the informed consent form; for patients aged <18 years, the inf... [+3]

Congenital cleft palate or submucous cleft palate. [+6]

Status: Recruiting

Lateral Pharyngoplasty Outcomes in Children Undergoing Tonsillectomy

The goal of this treatment study is to determine if doing lateral pharyngoplasty with tonsillectomy is better for children than doing tonsillectomy alone. The main questions it aims to answer are: * Do children experience less pain after surgery when lateral pharyngoplasty is performed with tonsillectomy compared to tonsillectomy alone? * Do children eat/drink better when lateral pharyngoplasty is performed with tonsillectomy compared to tonsillectomy alone? * Is there a lower risk of bleeding after tonsillectomy when lateral pharyngoplasty is performed? Researchers will compare children undergoing tonsillectomy and lateral pharyngoplasty with children undergoing tonsillectomy alone to see if the participants experience less pain, better oral intake, and less bleeding complications after surgery. Parents of participants will be asked to record pain scores and pain medications given, approximate amounts of daily oral intake, and any complications after surgery.

Participants needed: 160
Trial details
Age: 3-17Biological sex: AllType: InterventionalSponsor: Loma Linda UniversityUpdated: Feb 23, 2026Locations: 4
Eligibility criteria

Participants ages 3-17 years of age undergoing tonsillectomy +/- adenoidectomy a...

Subjects with congenital syndromes and/or developmental delay [+3]

Status: Not yet recruiting

Evaluation of the Effects of Adenoidectomy and Adenotonsillectomy on Voice in Children

This prospective study aims to evaluate the effects of adenoidectomy and adenotonsillectomy on voice and speech functions in children. Changes in voice quality and resonance may occur after the removal of adenoid and tonsillar tissues, particularly in pediatric patients with enlarged adenoids or tonsils. Objective voice assessments, including acoustic, aerodynamic, and nasalance measurements, as well as subjective voice-related quality of life questionnaires, will be performed before surgery and at the first and third months after surgery. The results of this study are expected to help clinicians better inform families about possible voice changes following adenoidectomy and adenotonsillectomy procedures.

Participants needed: 36
Trial details
Age: 4-13Biological sex: AllType: ObservationalSponsor: Gaziosmanpasa Research and Education HospitalUpdated: Feb 10, 2026Locations: 1
Eligibility criteria

Aged 4-13 years [+1]

Does not meet inclusion criteria [+10]

Status: Recruiting

Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia

The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.

Participants needed: 440
Trial details
Phase: Phase 4Age: 3-17Biological sex: AllType: InterventionalSponsor: Duke UniversityUpdated: Dec 5, 2025Locations: 1
Eligibility criteria

Age >= 3 and < 18 years [+4]

History of chronic kidney or liver disease [+3]

Status: Not yet recruiting

Self-assessment of Tonsil Size

The participants receive instructions on two tonsil size classification scales and then, using a tongue depressor as well as their mobile phone camera and/or a flashlight and a mirror, the participants assess the size of their own tonsils on two scales. After the self-assessment, a medical student and two ear, nose, and throat (ENT) specialists evaluate the participants' tonsil size using a tongue depressor and a headlamp, applying the same scales. The objective of this study is to demonstrate that patient self-assessment constitutes a sufficiently accurate method for evaluating tonsil size. Furthermore, it aims to show that patients experiencing conditions such as sleep apnea or swallowing difficulties can, on the basis of their own assessment, be appropriately referred to an otolaryngologist for surgical evaluation, thereby conserving healthcare resources and reducing the time burden for patients.

Participants needed: 90
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Turku University HospitalUpdated: Oct 3, 2025Locations: 1
Eligibility criteria

Experience in clinical work with patients [+1]

Status: Not yet recruiting

Tonsillectomy vs. Tonsillotomy in Adults With Obstructive Sleep Apnea

The primary purpose of this randomized controlled trial s to investigate whether surgical reduction of palatine tonsils (tonsillotomy) is a superior treatment compared to complete surgical removal of palatine tonsils (tonsillectomy) in adults patients with obstructive sleep apnea and concomitant enlarged tonsils in regards of perioperative and postoperative morbidity.

Participants needed: 464
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: University of AarhusUpdated: Apr 19, 2024
Eligibility criteria

Age > 18 years [+4]

Previous pharyngeal surgery such as previous tonsillotomy, tonsillectomy or pala... [+7]